antigen-binding fragment

antigen-binding fragment
"Fragment antigen binding." A monovalent antigen-binding fragment of an immunoglobulin molecule that consists of one light chain and part of one heavy chain, linked by interchain disulfide bonds.

Microbiology. . 2009.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Fragment antigen binding — The fragment antigen binding (Fab fragment) is a region on an antibody which binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. These domains shape the paratope the antigen binding… …   Wikipedia

  • Fragment antigen binding — …   Википедия

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia

  • fragment — A small part broken from a larger entity. acentric f. SYN: acentric chromosome. Brimacombe f. a ribonucleoprotein f. obtained by mild ribonuclease treatment of ribosomes. butterfly f. a broad triangular f. that is commonly present in …   Medical dictionary

  • Fab-Fragment — Strukturmodell eines Fab Fragments (Bändermodell). Das Fab Fragment, auch Fab Antikörper (von engl. Fragment antigen binding), ist das Antigen bindende Fragment eines Antikörpers, das durch Spaltung mit dem Enzym Papain gewonnen werden kann. Ein… …   Deutsch Wikipedia

  • Antigen processing — is a biological process that prepares antigens for presentation to special cells of the immune system called T lymphocytes. This process involves two distinct pathways for processing of antigens from an organism s own (self) proteins or… …   Wikipedia

  • Antigen-presenting cell — An antigen presenting cell (APC) or accessory cell is a cell that displays foreign antigen complexed with MHC on its surface. T cells may recognize this complex using their T cell receptor (TCR). Types APCs fall into two categories: professional… …   Wikipedia

  • Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) …   Wikipedia

  • Single chain variable fragment — (scFv) is a fusion of the variable regions of the heavy and light chains of immunoglobulins, linked together with a short (usually serine, glycine) linker.This chimeric molecule retains the specificity of the original immunoglobulin, despite… …   Wikipedia

  • Proliferating cell nuclear antigen — The assembled human DNA clamp, a trimer of the protein PCNA …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”